In this video, Dr. Sunil Gupta, Additional Director, NCDC, will discuss about the common practice of giving two antibiotics in combination. There are lot of fixed dose combination of antibiotics available in the market. Dr. Sunil will tell us that no just two but more than two combinations are also available. He will inform that few combinations are rational, for example, if penicillin is combined with beta lactamase inhibitors with is commonly known as amoxiclav or augmentin. He will describe other rational fixed combinations of antibiotics. He will further discuss that except for these rational combinations, other combinations of antibiotics should not be used.