A combination of statins/statin plus ezetimibe is recommendedin all adults over the age of 40 years with chronickidney disease (CKD) stage 3 or higher.In adults between the ages of 18 and 39 with CKD shouldbe treated with statins if they have on..Read More

Dear Colleague,On behalf of the Lipid Association of India (LAI), the organizing committee feels privileged to welcome you to the LAICON INTERNATIONAL 2022 in the city with a rich cultural heritage, New Delhi. As you are aware, the conference is..Read More

Therapeutic lifestyle Prescription includes Dietary Modifications, Physical activity/exercise, weight loss, smoking, tobacco cessation, alcohol and stress management.Mediterranean diet is high in fruits, vegetables, bread and other forms of cere..Read More

No doubt, Atherosclerotic Cardiovascular Disease (ASCVD) risk rises as the levels of Low-density Lipoprotein Cholesterol (LDL-C) and Non-high-density Lipoprotein Cholesterol (non HDL-C) increase, and that the risk decreases as the levels of LDL-..Read More

Peripheral artery disease (PAD) is a highly prevalent atherosclerotic syndrome and is associated with significant disability, morbidity and mortality.PAD still largely remains underdiagnosed, understudied and undertreated.Despite the significant..Read More

Atherosclerosis is a preventable disorder.LDL-C plays a central role in Atherosclerosis, Epidemiological, Observational studies, Genetic studies and randomized control trials have shown the impact of LDL as the Culprit.The more the reduction of ..Read More

Genetic causes of Hypertriglyceridemia (HTG) such as Lipoprotein Lipase (LPL) Deficiency should be considered in severe HTG cases where multiple drug Pharmacotherapy and aggressive dietary modifications fail to optimize Triglyceride (TG) levels...Read More

Ischemic heart disease (IHD) is the most important cause of disease burden and premature mortality in India.The IHD burden is increasing, in contrast to most high and middle-income countries.There is significant geographic variation in its incid..Read More

Chronic kidney disease (CKD) is a vital risk factor for coronary artery disease (CAD).Advance CKD is associated with high CV mortality related to CAD and nonatherosclerotic cardiac disease.LAI recommends using statins in patients with CKD stage ..Read More

Most MIs occurs in young patients without risk factors; 1.1 million patients <55 years with MI.Multiple non-traditional risk factors for ASCVDFrailty, ADL, glaucoma, arthritis, sinusitis, incontinence, social dependence for personal care.Risk..Read More

Familial hypercholesterolemia (FH) is one of the most common and single severe gene disorders, affecting approximately 30 million people worldwide.One baby with FH is born globally every minute.While statins and ezetimibe constitute first-line t..Read More

Hyperlipidemia/Dyslipidemia investigations:Tests that establish primary/secondary cause for Hyperlipidemia/DyslipidemiaTests that establish additional risks related to DyslipidemiaLipid-relatedNon-lipid-related Dyslipidemia Investigations:B..Read More

Triglycerides (TGs) consist of fatty acids linked to one glycerol.TGs are transported as core constituents of all lipoproteins.TGs are hydrolyzed by LPL.Pathogenic mutations in LPL, ApoC2, GPIHBP1, LMF1 and ApoA-V are the causes of monogenic chy..Read More

Preventive cardiology efforts begin with assessment of CVD risk.Despite many available risk assessment approaches, a substantial gap remains in the detection of asymptomatic individuals who ultimately develop CHD.Most MIs are caused by low-grade..Read More

HDL is complex and has multiple functions.HDL deficiency is mostly secondaryHDL cholesterol efflux and anti-inflammation actions relevant to outcomes.New methods (e.g., MUS studies) are required to assess HDL-related therapies...Read More

Coronary artery calcification (CAC) has emerged as the most predictive single CV risk marker in asymptomatic individuals capable of adding predictive information beyond the traditional risk factors.CAC scoring appears to be useful for making dec..Read More

High levels of lipoprotein are an independent causal risk factor for ASCVDs.Mechanisms include increased atherogenesis, inflammation and thrombosis.Lipoprotein(a) [Lp(a)] is predominantly a monogenic CV risk determinant, with =70% to ≥90% of i..Read More

Statins remain first-line drugs for diabetic dyslipidemia management.Lowering the LDL-C to the desired level is based upon the risk category (LAI Guidelines).Despite adequate statin therapy, residual CHD risk factor remains.Nonstatin drugs to fu..Read More

Statin Intolerance is defined as “one or more adverse effects associated with Statin therapy, which resolves or improved with dose reduction or discontinuation.”Liver Injury is very rarely associated with Statins.Patients of Diabetes with or..Read More