1. Most MIs occurs in young patients without risk factors; 1.1 million patients <55 years with MI.
2. Multiple non-traditional risk factors for ASCVD
a) Frailty, ADL, glaucoma, arthritis, sinusitis, incontinence, social dependence for personal care.
3. Risk enhancing factors for clinician-patient risk discussion
a) Family history of premature ASCVD
b) Primary hypercholesterolemia
c) Metabolic syndrome
d) Chronic kidney disease (CKD)
e) Chronic inflammatory conditions
f) History of premature menopause and history of a pregnancy-associated condition that increases later ASCVD risk
g) Lipid biomarkers associated with increased ASCVD risk.
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