In this video, Dr. Sunil Dargar, MBBS, MD, Pathologist, New Delhi will talk about how to diagnose tuberculosis. While dealing with the diagnosing of tuberculosis, new tests do help but the old dictum of finding the mycobacterium tuberculosis which is the simplest, safest, and fastest and the most economical way of diagnosing tuberculosis. If pleural fluid or abdominal fluid or any other cavity’s fluid is collected then it has to be sent for culture test for mycobacterium tuberculosis. Before sending the fluid for culture test, it needs to be centrifuged and the sediments should be stained with Ziehl–Neelsen stain. The culture reports comes after 3 -5 weeks. Based on these methods, a safe treatment schedule can be planned accordingly for atypical or typical mycobacterium tuberculosis.