ChallengesInadequate response in those at high-risk or those with very high low-density lipoprotein cholesterol (LDL-C) levels. Intolerance to av..
ODYSSEY OUTCOMES trialCompared with placebo in patients with recent acute coronary syndrome (ACS), alirocumab 75 or 150 mg subcutaneous Q2W targe..
Risk assessmentHigh-risk group: Atherogenic dyslipidemia, MetS, diabetes, genetics, Lp(a), diet, visceral adiposity and environment.TestingQRISK3..
During the first-month post-ACS, the risk of cardiovascular (CV) events is the highest.Trials of high-intensity statins have shown a reduction in..
Uniformity in the use of dyslipidemia guidelines to be emphasized as patients in India often consult many physicians over time: to avoid contradi..
Statins are the most common, widely prescribed first choice medication for lipid-lowering.Inability to take statins to achieve the target LDL-C f..
The CV event rates in elderly subjects are proportionately higher than for younger subjects in primary and secondary prevention studies emphasizi..
Nonalcoholic fatty liver disease (NAFLD) is associated with metabolic factors, and insulin resistance, type 2 diabetes and CVD are the most commo..
Diabetic dyslipidemia is characterized by hypertriglyceridemia, high levels of apoB, non-HDL-C and small-dense LDL particles.Moderate- to high-in..
What to measure?Lab results: TGs, remnant cholesterol, non-HDL-C.What you estimate?TGs in remnants + LDL + HDL; remnant cholesterol, cholesterol ..
Both are worthy and detailed but may be far too complex for general use.Why were the simple communication tools for young people of relative risk..
Stroke is a leading cause of morbidity and mortality.Relationship between stroke, lipids and statins is complex. The benefits of statins in prima..
Although a number of questions remain unanswered, the available evidence supports that statins do increase the chances of type 2 diabetes mellitu..
There are currently no sex-specific guidelines for the evaluation and management of lipids.Lipids are impacted by normal hormonal changes in wome..
Unanswered questionsIf statins are beneficial, is it due to lipid-lowering or “pleiotropic” effects?Is the benefit similar in ischemic vs. no..
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