Statins in Heart Failure: More Questions Than Answers

Statins in Heart Failure: More Questions Than Answers

Unanswered questions

  • If statins are beneficial, is it due to lipid-lowering or “pleiotropic” effects?
  • Is the benefit similar in ischemic vs. nonischemic heart failure?
  • Is low cholesterol associated with poor outcomes in heart failure?
  • Could statins actually be detrimental?
  • Does the dose of statins matter? (No effect in HF benefit in CARE, PROSPER, ALLHAT, ASCOT)

Statins in CVD

  • Well-proven benefit of statins in reducing CV events:

o Primary prevention – WOSCOPS, AFCAPS/TexCAPs, ALLHAT

o Secondary prevention – 4S, CARE.

  • Intensive statin therapy may be superior to moderate statin therapy

o PROVE IT-TIMI 22, TNT, IDEAL, A2Z.

Dr. Ameet G Sattur

Dr. Ameet G Sattur is a Consultant Interventional Cardiologist at Sattur Heart Care. He has completed his MBBS at JN Medical College, Belgaum. He finished his MD - (General Medicine) at Kasturba Medical College, Manipal and DM - (Cardiology) at JN Medical College, Belgaum. He has delivered a number of lectures at local, State, National and International Conferences.

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