Evidence for Intensive LDL-C-lowering for the Acute Coronary Syndrome

Evidence for Intensive LDL-C-lowering for the Acute Coronary Syndrome

  • During the first-month post-ACS, the risk of cardiovascular (CV) events is the highest.
  • Trials of high-intensity statins have shown a reduction in MACE in the acute, early and late phases of ACS.
  • The level of LDL-C is directly linked to the amount of plaque stabilization and the number of CV events.
  • High-intensity statins with ezetimibe should be started at emergency triage.
  • An extended lipid profile should be measured in emergency triage and repeated at weeks 2 and 4.
  • Identify the ASCVD risk category and LDL-C target per the LAI recommendation.
  • Plan a combination of lipid-lowering medications to achieve the LDL-C target.
  • All ASCVD risk factors should be controlled, and lifestyle interventions implemented.

Dr. Raman Puri

Dr. Raman Puri is an experienced Interventional Cardiologist with 39+ years in the field. He is a Fellow in Cardiology, National Cardiovascular Centre, Osaka, Japan, and also a Clinical Fellow in Interventional Cardiology Hospital Charles, Nicolas, France. He has written several publications in reputed international as well as national medical journals.

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