According to the evidence, people with Atherosclerotic Cardiovascular Disease (ASCVD) are a Heterogeneous Population, with some having a higher r..
Heart failure (HF) is a serious problem in India with high mortality, a high rate of recurrent hospitalization and poor quality of life.Four foun..
The National Medical Commission (NMC) has formulated NMC guidelines 2022 for medical professionals to follow in their professional activities. Th..
Lipoprotein apheresis is a very efficient but time consuming and expensive method of lowering levels of LDL-C, lipoprotein(a) [Lp(a)] and other a..
Cardiovascular disease is the leading cause of death, attributing to 28% of the total mortality in the Indian population with an average age of o..
Cardiovascular disease in India is challenging as it occurs at a young age.Dyslipidemia is one of the biggest risk factors for CVD.Statins are an..
LDL-C is universally accepted as a major driver of atherosclerosis. Higher the baseline LDL, the higher the risk.Low and very low LDL levels are ..
Modern registries have emerged as one of the important clinical research tools for understanding a disease in all its dimensions and the influenc..
Substantial ASCVD risk persists despite low levels of LDL-C and elevated TGs, and their remnants account for a portion of this residual risk.Comb..
High blood pressure (BP) is the most important cause of global mortality and morbidity.Management of hypertension should move away from the “nu..
Heart failure is extremely frequent, often forgotten and fatal in diabetes.Diabetes changes the cardio-metabolic fingerprints leading to a predis..
Measurement of LDL-C and HDL-C are inaccurate, so why measure?All the apoB-containing particles are atherogenic; the measurement of apoB encompas..
Therapy for severe FH:Pharmacotherapy – lipid-modifying drugsExtracorporeal removal of LDL-apheresisSurgical therapy – portacaval shunt, part..
Studies show 15% to 25% LDL-C reduction on background statin therapy; higher LDL-C reduction in patients not on statins.Combination of bempedoic ..
Nonfasting samples can be used to measure total cholesterol (TC), HDL-C and HDL-C.TG can be measured in a nonfasting state, but reference interva..
Familial hypercholesterolemia is a highly atherogenic disorder.The risk of CHD is increased 10- to 20-fold.Phenotype is highly variable.Genetic t..
ASCVD risk remains high in patients who have attained the guideline – recommended LDL-C goals.In some circumstances like diabetes, obesity or v..
Preventive cardiology efforts begin with the assessment of CVD risk.Risk assessment algorithms include the European SCORE, PROCAM, QRISK, FRAMING..
Familial hypercholesterolemia has been considered as one of the major causes of premature ASCVD, with carotid ultrasound being one of the most po..
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