Trial of Labor after Cesarean in Obese Patients Linked to Higher Maternal Risks
Published On: 17 Oct, 2025 11:53 AM | Updated On: 06 Dec, 2025 3:52 AM

Trial of Labor after Cesarean in Obese Patients Linked to Higher Maternal Risks

 A large population-based study of 794,278 obese women with a prior cesarean delivery has found that those who attempted a trial of labor after cesarean (TOLAC) faced a higher rate of composite maternal adverse outcomes (CMAO) compared with those who underwent a planned repeat low transverse cesarean section (RLTCS). Of the total cohort, 126,809 attempted TOLAC and 667,469 had planned RLTCS. The risk of serious maternal complications—including ICU admission, uterine rupture, hysterectomy, or transfusion—was 9.0 per 1,000 births for TOLAC versus 5.3 per 1,000 for RLTCS (adjusted risk ratio 1.64; 95% CI, 1.53–1.75).

Although the absolute increase in risk was modest, the findings suggest that TOLAC in obese patients is associated with greater maternal morbidity. The authors emphasize the importance of individualized counseling and careful risk–benefit assessment when considering labor after cesarean in this population.

Reference: Jude G, Fain A, Raker C, et al. The association between trial of labor after cesarean in obese patients and adverse maternal outcomes. Arch Gynecol Obstet. 2024;309:2421–2426. doi:10.1007/s00404-023-07113-6

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