Nuchal Translucency as a Predictor of Congenital Heart Defects in Early Pregnancy
Published On: 22 Oct, 2025 3:31 PM | Updated On: 18 Dec, 2025 3:23 AM

Nuchal Translucency as a Predictor of Congenital Heart Defects in Early Pregnancy

A recent observational study by Rema V Nair and colleagues evaluated the accuracy of nuchal translucency (NT) in detecting congenital heart defects (CHDs) at 11 to 13+6 weeks of gestation. The study included 150 singleton pregnancies. Participants varied in age, with 14% ≤20 years, 20% between 21–25 years, 34.6% between 26–30 years, 20% between 31–35 years, and 11.3% over 35 years. It was observed that 45.3% were primigravida, and 54.6% were multigravida. 

NT measurement showed high predictive value, with a sensitivity of 100%, specificity of 93.9%, and a negative predictive value of 100%. The study concluded that increased NT thickness is a key factor for identifying fetuses requiring specialized echocardiography. 

When abnormal ductus venosus doppler flow is observed with increased NT, the risk of CHD is higher, making it essential to rule out CHD as early as possible. Accurate NT assessment facilitates the timely identification and management of CHDs, improving prenatal care outcomes.

Reference:

Nair RV, Jameela Ponmalar AR, Ramya VA, Kavitha CM. Fetal nuchal translucency–a screening tool in predicting congenital cardiac abnormalities. Age.;20:21-5.

https://journal.barpetaogs.co.in/pdf/112234.pdf

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