COVID Protocol 1:- What to do on Day 1 (Confirmed/Suspect/Probable)

DAY ONE: CONFIRMED/SUSPECT/PROBABLE

Day one means that the patient may have confirmed, probable, or suspected Covid-19 infection. Suspect means that the patient may have a very high degree of suspicion means he/she has come in contact with somebody. Probable means that the patient is not a positive case of Covid-19 but having classical symptoms and confirmed means the patient is already a confirmed case of Covid-19.

The first test to be done is CRP that is done in mg/L that is from the baseline CRP, simultaneously with CRP CBC is also done in which neutrophils to lymphocytes ratio is tested.

Serum IgG antibody test is also performed and finally RT-PCR or RAT test. CRP tells the severity of inflammation in the body and if CRP>10 it indicates pneumonia or systemic inflammation.

If the N/L ratio> 3.18 it is observed whether neutrophils increased or lymphocytes decreased as increased N indicates TH-17 inflammation and low L indicates TH-1 inflammation. If serum IgG antibodies are already present in the body it indicates re-infection.

Positive RT-PCR indicates confirmed Covid-19 infection but it does not tell that whether Covid-19 infection was in past or present as sometimes it can be positive for 3 months.

If RAT is negative with positive RT-PCR then there are chances that the patient is not infected.

A higher cT value in RT-PCR shows a low infection, If the E gene is negative and other genes are positive it indicates E gene target failure while E and RDRP gene test are positive with S gene failure then it is U.K. strain. If the cT value is very low it is also the suspect of U.K. strain.

The patient should take Ivermectin 12 mg, Doxycycline 100mg, and colchicine as a treatment on the first day of infection after consulting the doctor.

There are two types of CRP tests qualitative and quantitative, qualitative indicates positive or negative CRP, and if CRP< 6mg/L it shows low-grade inflammation.