Analysis of a Case Report of Sclerosing Stromal Tumors in Young Women

Sclerosing stromal tumors (SSTs) are uncommon ovarian tumors that primarily affect young women in their 20s and 30s. This report details the case of a young woman diagnosed with an ovarian SST, focusing on its clinical features, histopathological findings, and treatment approach.

Due to their rarity and diverse symptoms that can resemble other ovarian tumors, diagnosing SSTs can be challenging. Patients often report vague symptoms such as abdominal discomfort, bloating, and irregular menstrual cycles. Accurate diagnosis relies on imaging studies and histopathological analysis.

SSTs are distinguished histologically by a growth of fibrous stromal cells mixed with varying levels of collagen and hyalinization, complicating the diagnostic process. Immunohistochemical techniques are essential for confirming the diagnosis.

Surgical removal is the primary treatment, aiming for complete excision while trying to preserve ovarian function. Intraoperative frozen section analysis supports decision-making during surgery. Because SSTs are typically benign, additional therapies are usually unnecessary.

Therefore, a collaborative approach involving gynecologists, pathologists, and radiologists is vital for the accurate diagnosis and effective management of SSTs, leading to better outcomes for patients. Ongoing research is needed to better understand the causes of SSTs and improve treatment strategies for these rare tumors.

Source: Madhuri TS, Sharma N. Case report: Sclerosing stromal tumor in a young female: Clinical presentation and management. Indian J Obstet Gynecol Res 2025;12(1):159-163, https://doi.org/10.18231/j.ijogr.2025.029.