15 Seconds to Safety: PVP-I's Virucidal Efficacy

The present study investigated various formulations of povidone-iodine, including skin cleanser, surgical scrub, and gargle/mouthwash, for their in vitro virucidal efficacy. 

The study assessed the reduction in virus titer, equivalent to a >/=4 log10 decrease (indicating a 99.99% inactivation), as an indicator of virucidal activity. Notably, this significant reduction was observed within 15 seconds of applying each undiluted PVP-I product, demonstrating efficacy under clean and dirty conditions.

The findings underscore the effectiveness of PVP-I in hand wash products designed for potentially contaminated skin and PVP-I gargle/mouthwash for reducing viral load in the oral cavity and oropharynx. 

This study suggests that incorporating PVP-I-based hygiene measures, like gargling, may be instrumental in preventing the transmission of respiratory viruses.


Eggers M, Eickmann M, Zorn J. Rapid and Effective Virucidal Activity of PovidoneIodine Products Against Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and Modified Vaccinia Virus Ankara (MVA). Infect Dis Ther. 2015. DOI 10.1007/s40121-015-0091-9


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