Unmasking the Risks of PCOS: A Cross-Sectional Insight

Polycystic Ovary Syndrome (PCOS), long recognized for its reproductive implications, also poses substantial risks for long-term metabolic and cardiovascular health. Findings from a cross-sectional study comparing 200 women with PCOS to 300 age-matched controls highlight this broader burden. Women with PCOS demonstrated significantly higher rates of insulin resistance (72% vs. 25%) and Type 2 diabetes (35% vs. 10%), underscoring the strong metabolic link. Cardiovascular risk markers, such as hypertension, dyslipidemia, and elevated C-reactive protein, were also markedly elevated in the PCOS group. Notably, 45% had hypertension and 60% had abnormal cholesterol profiles, compared to 20% and 30% in controls, respectively. Fertility issues, particularly anovulation and infertility, affected the majority of women with PCOS. These findings emphasize the need to view PCOS not only as a reproductive disorder but as a chronic multisystem condition requiring integrated care. Comprehensive management through lifestyle interventions, pharmacotherapy, and routine monitoring is critical to reducing long-term disease risk and improving quality of life in affected women.

Source: Yadav, S. K., Rai, A., Gupta, A., &Kumari, R. (2025). Long-term implications of polycystic ovary syndrome (PCOS): An in-depth study on associated health risks and complications. Indian Journal of Obstetrics and Gynecology Research, 12(1), 74–78. https://doi.org/10.18231/j.ijogr.2025.014