The Correlation between Chlamydia Trachomatis and Female Infertility: A Systematic Review

We still lack knowledge about the impact of Chlamydia trachomatis (CT) infection on female fertility since the level of evidence associating these factors is weak. Hence, a recent review better elucidated this matter.

The study's authors searched the electronic database like Medline/PubMed for relevant studies in the previous five years. It searched for keywords like chlamydia trachomatis AND infertility; chlamydia trachomatis AND tubal alteration AND infertility; chlamydia AND low pregnancy rates.

After scrutinizing the available studies for relevancy, the authors included 17 studies for qualitative analysis.
Their systematic review verified the hypothesis that CT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them.

Thus there exists an important association between CT infection and female infertility. Therefore CT screening as a part of the infertility investigation routine is relevant and has a reasonable justification.

Passos LG, Terraciano P, Wolf N, Oliveira FDS, Almeida I, Passos EP. The Correlation between Chlamydia Trachomatis and Female Infertility: A Systematic Review. Rev Bras Ginecol Obstet. 2022 Jun;44(6):614-620. English. doi: 10.1055/s-0042-1748023. Epub 2022 May 16. PMID: 35576969.

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