For screening high risk-populations Fib-1 is the First-line of Defense. Sequential or combination testing can be done to address the Grey Zone.
For identification of at-risk NASH, use the FibroScan-AST (FAST), MRI-aspartate aminotransferase (MAST), MR elastography combined with FIB-4 (MEFIB) or Agile 3t (F3 fibrosis).
To assess response to Resmetirom - check for a 30% reduction in MRI proton density fat fraction (MRI-PDFF), Pro-C3/C3M ratio and vibration-controlled transient elastography (VCTE). For evaluating progression to cirrhosis check for VCTE >16.6 kPa, ELF >9.75.
For predicting MALO check if ELF >11.27, VCTE >30.7 kPa, cT1 >875 ms, MAST >0.24, ME-FIB + (MRE ≥3.3 and FIB-4 ≥1.6). Longitudinal changes over time are more important than a single cross-sectional view. Use FIB-4, VCTE and MR elastography
Subscribe To Our Newsletter
Filter out the noise and nurture your inbox with health and wellness advice that's inclusive and rooted in medical expertise.
Medtalks is India's fastest growing Healthcare Learning and Patient Education Platform designed and developed to help doctors and other medical professionals to cater educational and training needs and to discover, discuss and learn the latest and best practices across 100+ medical specialties. Also find India Healthcare Latest Health News & Updates on the India Healthcare at Medtalks
Please update your details