Patients with significant presentations of alopecia experience significantly harmful effects, both physical and psychological. Oral minoxidil is suggested by dermatologists as potential remedy across the world.
In patients being treated for hair loss, minoxidil is the standard therapy of choice. In a study, it was reported that 5% minoxidil solution, significantly increased the index of hair density in patients (16%) when compared with platelet-rich plasma (PRP) therapy. Besides, minoxidil does not alter testosterone levels or adrenal-androgenetic secretion, nor did it change the genetically programmed sensitivity of hair follicles to androgens.
A recent study has suggested that a synergistic activity was seen when minoxidil was used along with PRP with high clinical efficacy of the complex therapy. While PRP is a promising treatment for androgenetic alopecia, and minoxidil is the first line therapy; the combined PRP and minoxidil use appears promising for the treatment of androgenetic alopecia.
Pakhomova EE, Smirnova IO. Int J Mol Sci. 2020 Sep; 21: 6516.
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