Most liver diseases, especially NAFLD, are characterized by an abnormal accumulation of triglyceride in hepatocytes. Hepatic de novo lipogenesis may play an important role in the accumulation of lipids in the liver during NAFLD. On the other hand, the initiation and progression of liver fibrosis heavily rely on excessive activation of hepatic stellate cells (HSCs). In this video, let's take a quick look at the role of de novo lipogenesis and hepatic stellate cells in liver disease.
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