Chemotherapy-induced
nausea and vomiting (CINV) adversely affect the quality of life (QoL) of pediatric
cancer patients. Despite standard guidelines for prevention, suboptimal control
of emesis persists in clinical practice. Nausea assessment in children is
challenging due to its subjective nature and the lack of validated tools.
The original Pediatric
Nausea Assessment Tool (PeNAT)-English, validated for children aged 4-18 years,
employs a standard script and visual scale to help children differentiate
nausea from vomiting. For this study, PeNAT was translated and adapted to Hindi
– considering the linguistic diversity in India.
The findings
demonstrated good reliability and validity of PeNAT-Hindi, allowing children to
differentiate between nausea and vomiting across various factors, except in the
9 to <13years subgroup. The tool proved effective in assessing severity and
discriminating pain from nausea. However, responsiveness was modest due to a
short follow-up period post-chemotherapy.
PeNAT-Hindi can be utilized in clinical practice and research to determine nausea prevalence and severity, aiding tailored CINV prophylaxis in the Hindi-speaking Indian population. The need for more language-specific psychometric evaluations in the Indian context, especially considering cultural and language barriers, is emphasized. Furthermore, the translation and psychometric evaluations could be extended to other studies involving cancer patients' QoL, survivors, and the psychological impact on parents.
Source: Peyam S, Bansal D. Indian
Journal of Pediatrics. 2024 Feb;91(2):117-8.
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