Novel agents with novel action: A new therapeutic horizon in diaper dermatitis

The present study discussed novel combinations of topical agents (i.e., zinc gluconate, zinc oxide, dexpanthenol, and taurine) that target a combination of mechanisms in diaper dermatitis.

A literature search of the relevant published studies screened 207 related articles, which were categorized, summarized, and presented as-

• Diaper dermatitis aka diaper rash, napkin dermatitis, and nappy rash, is the commonest skin eruption in infants and toddlers. 
• The past few years have witnessed several technologic advances in diaper design to ease the severity of diaper dermatitis symptoms. However, the unique environment of the diaper area has continued to cause recurring symptoms of diaper dermatitis in both children and adults. 
• Commercially available products, as well as certain home remedies, are regarded as effective in managing sensitive and delicate skin in the diaper area. 
• These topical agents form a protective barrier over the skin and relieve the effect of external irritants, which cause the reddening and burning sensation often associated with diaper dermatitis.

These therapeutic strategies may help in preventing and controlling diaper dermatitis.

Source: Hebert AA. A new therapeutic horizon in diaper dermatitis: Novel agents with novel action. Int J Womens Dermatol. 2021;7(4):466-470. Published 2021 Feb 16. doi:10.1016/j.ijwd.2021.02.003