Pneumonia makes the top infectious cause of death in children, with especially high mortality in low- and middle-income countries. Interleukin-18 binding protein (IL-18BP), a natural antagonist of the proinflammatory cytokine interleukin-18, is raised in numerous autoimmune conditions and infectious diseases.
This prospective cohort study determined the association between admission IL-18BP levels and clinical severity among children admitted to two hospitals in Uganda for hypoxemic pneumonia. It included a total of 42 children (median age of 1.2 years). And found that-
This study shows that higher IL-18BP levels are associated with increased disease severity and prolonged recovery times in children with pneumonia.
Cytokine. 2022 Feb;150:155775. doi: 10.1016/j.cyto.2021.155775. Epub 2021 Dec 5. PMID: 34875584.
Subscribe To Our Newsletter
Filter out the noise and nurture your inbox with health and wellness advice that's inclusive and rooted in medical expertise.
Medtalks is India's fastest growing Healthcare Learning and Patient Education Platform designed and developed to help doctors and other medical professionals to cater educational and training needs and to discover, discuss and learn the latest and best practices across 100+ medical specialties. Also find India Healthcare Latest Health News & Updates on the India Healthcare at Medtalks
Please update your details
Please login to comment on this article