There may be the existence of common inflammatory biomarkers linking obesity and asthma in children. However, laboratory and clinical characteristics of children with obesity and asthma remain still poorly defined.
A recent study investigated lung function and the cytokine profile in children with obesity and asthma. This prospective, cross-sectional pilot study compared the pulmonary function tests, biochemical parameters, and serum cytokines levels in three groups of 28 children each, matched for age and sex.
This study explains that children with obesity and asthma have the most striking cytokine profile, suggesting a pro-inflammatory role of fat mass in asthma development.
Maffeis L, Agostoni CV, Marafon DP, et al., Cytokines Profile and Lung Function in Children with Obesity and Asthma: A Case Control Study. Children. 2022; 9(10):1462. https://doi.org/10.3390/children9101462
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