There are various mechanisms of SARS-CoV-2 infection and COVID-19 immunopathogenesis. Therapies inhibiting viral infection and regulation of dysfunctional immune responses may synergize to block pathologies at multiple steps. Immune dysfunction and disease severity in COVID-19 patients should be considered when developing and evaluating vaccines. Further research is needed on the host immune response to SARS-CoV-2, particularly the drivers of healthy versus dysfunctional outcomes. These will assist identify immunological correlates of protection and disease severity for optimal patient triage.
President Heart Care Foundation of India and Group Editor in Chief MEDtalks
Recipient of Padma Shri, Vishwa Hindi Samman, National Science Communication Award and Dr B C Roy National Award, Dr Aggarwal is a physician, cardiologist, spiritual writer and motivational speaker. He was the Past President of the Indian Medical Association and President of Heart Care Foundation of India. He was also the Editor in Chief of the IJCP Group, Medtalks and eMediNexus
Diabetologist in MEDI Care Hospital, Indore
Dr Rajesh Agrawala is a Diabetologist in MEDI Care Hospital, Indore.
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